iJMJD6
Product Sizes
5 mg
£173.00
10-4039-5MG
25 mg
£325.00
10-4039-25MG
About this Product
- SKU:
- 10-4039
- Additional Names:
- WL12
- CAS Number:
- 899548-78-8
- Extra Details:
- Inhibitor of the arginine demethylase JMJD6 (IC50 = 220 nM) with selectivity over other JmjC domain-containing proteins.1 Exhibited antiproliferative effects in HeLa (EC50 = 1.49 uM), SMCC7721 (EC50 = 9.37 uM), and MCF7 (EC50 = 9.53 uM) cells.2 Displayed no cytotoxicity towards normal cervical, liver, and breast epithelial cells. iJMJD6 significantly suppressed tumor growth in a HeLa, SMCC7721, MCF7, MDA-MB-231, U87, and HCT116 mouse xenograft models.2
- Immunogen:
- Protein demethylase
- Molecular Weight:
- 277.28
- Physical State:
- Solid
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
