A-196
Product Sizes
5 mg
£193.00
10-4018-5MG
25 mg
£407.00
10-4018-25MG
About this Product
- SKU:
- 10-4018
- Extra Details:
- A-196 (1982372-88-2) is a potent and selective (over 29 other methyltransferases) inhibitor of the protein lysine methyltransferases SUV420H1(IC50 = 25 nM) and SUV420H2 (IC50 = 144 nM). It substantially inhibited non-homologous end-joining (NHEJ)-directed DNA repair but not homology-directed repair(HDR) in cells treated with ionizing radiation. A-196 is active in cells and displayed no toxicity in several cell lines.
- Molecular Weight:
- 359.25
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://focusbiomolecules.com/dna-damage/a-196-suv420h1-h2-methyltransferase-inhibitor/