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Product Sizes
5 mg
£204.00
10-4003-5MG
25 mg
£466.00
10-4003-25MG
About this Product
SKU:
10-4003
Additional Names:
ACR16
Extra Details:
Pridopidine is being studied as a potential treatment for Huntington's disease, Parkinson's disease, and schizophrenia based on its locomotor stabilizing and antipsychotic-like effects.1,2 It was, unusually, able to reverse both hypo- and hyperdopaminergia depending on local dopamine concentrations without inducing catalepsy. This was originally attributed to functional dopamine D2 antagonism with fast on/off kinetics ("dopamine stabilizer").3 More recent studies have attributed pridopidine's effects to its being a more potent sigma-1 ligand than a D2 ligand.4,5 Displays neuroprotective/restorative effects6,7 and ameliorates central features of amyotrophic lateral sclerosis pathology8 in a sigma-1-mediated manner
Molecular Weight:
281.41
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
RT
Supplier:
Focus Biomolecules
Type:
Biomaterials: Ligands