Stiripentol
Product Sizes
10 mg
£158.00
10-3978-10MG
50 mg
£267.00
10-3978-50MG
About this Product
- SKU:
- 10-3978
- Additional Names:
- BCX2600
- CAS Number:
- 49763-96-4
- Extra Details:
- Stiripentol is a clinically useful anticonvulsant used to treat Dravet syndrome. The precise mechanism of action is unknown but it is thought to act via increasing GABAergic activity1, inhibiting LDHA2 and thereby activating ATP-sensitive potassium channels, and blocking Na+ and Ca2+ channels3. It also inhibits the cytochrome P450 enzymes 1A2, 2C9, 2C19, 2D6, and 3A4.4 Stiripentol and the copper ionophore elesclomol (Cat#10-4238) synergistically suppressed esophageal squamous cell carcinoma (ESCC) tumor growth.2 Lactate dehydrogenase A inhibition by stiripentol reduced ESCC cuproptosis resistance by inhibiting lactylation of NUDT21.
- Immunogen:
- Cytochrome/MDR|Dehydrogenase (GAPDH, GPDH, IMPDH, PHGDH, LDH, DHODH, ALDH, GDH, IDH, UGDH, DPD, DHPDH, KGDH, PDH, and MDH)|Ion channel
- Molecular Weight:
- 234.3
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
