C19-9
Product Sizes
5 mg
£149.00
10-3977-5MG
25 mg
£195.00
10-3977-25MG
About this Product
- SKU:
- 10-3977
- Additional Names:
- (E)-N'-(3-Hydroxy-4-methoxybenzylidene)-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide
- CAS Number:
- 1477482-47-5
- Extra Details:
- C19-9 (1477482-47-5) is a novel non-RGD inhibitor of the integrin A AlphavB Beta3 receptor (KD = 102 nM). It was active against the human prostate carcinoma epithelial cell line 22RV1 (IC50 = 467 nM) and human prostate cancer organoids (IC50 = 652 nM). C19-9 was active in vivo in 22RV1 mouse xenografts and blocked growth in enzalutamide-resistant mouse CRPC xenografts.
- Molecular Weight:
- 314.35
- Physical State:
- Solid
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
