Brequinar sodium
Product Sizes
10 mg
£158.00
10-3965-10MG
50 mg
£315.00
10-3965-50MG
About this Product
- SKU:
- 10-3965
- Additional Names:
- DuP-785|NSC 368390
- CAS Number:
- 96201-88-6
- Extra Details:
- Brequinar sodium is an inhibitor of dihydroorotate dehydrogenase (DHODH)1,2 with IC50's between 0.2 and 5.8 uM in various cell lines3 and 20 nM in isolated enzyme4. It reduced leukemic cell burden, decreased levels of leukemia-initiating cells, and improved survival in human and mouse models of acute myeloid leukemia.4 Brequinar displayed broad antiviral activity against flaviviruses, positive-strand RNA alphaviruses, negative-strand RNA rhabdoviruses, Influenza A and B viruses, and HIV.5,6,7
- Immunogen:
- Dehydrogenase (GAPDH, GPDH, IMPDH, PHGDH, LDH, DHODH, ALDH, GDH, IDH, UGDH, DPD, DHPDH, KGDH, PDH, and MDH)
- Molecular Weight:
- 397.35
- Physical State:
- Solid
- Purity:
- 99%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
