PT-179
Product Sizes
5 mg
£168.00
10-3963-5MG
25 mg
£291.00
10-3963-25MG
About this Product
- SKU:
- 10-3963
- CAS Number:
- 2924858-25-1
- Extra Details:
- PT-179 is an orthogonal thalidomide analog that binds cereblon (CRBN: KD = 587 nM; pomalidomide KD = 500 nM) with greatly reduced off-target activity compared to pomalidomide. Pomalidomide induced differential expression of 1426 genes in MM.1S multiple myeloma cells compared to only 3 for PT-179. PT-179 is an interesting new tool for exploring CRBN-based therapeutics.
- Immunogen:
- Molecular glue|Ubiquitin ligase
- Molecular Weight:
- 343.34
- Physical State:
- Solid
- Purity:
- >98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Sell Sheet 1:
- View Sell Sheet Here
