Tafamidis
Product Sizes
5 mg
£158.00
10-3743-5MG
25 mg
£243.00
10-3743-25MG
About this Product
- SKU:
- 10-3743
- Additional Names:
- PF-06291826
- CAS Number:
- 594839-88-0
- Extra Details:
- A potent and selective transthyretin (TTR) kinetic stabilizer. It binds selectively and with negative cooperativity to the two normally unoccupied thyroxine binding sites of the TTR tetramer (Kd = ~2 and ~200 nM)1. Stabilizes wild-type and mutant TTR under varying conditions in vitro (EC50=2.7-3.2 M).1 Clinically useful for the treatment of familial amyloid polyneuropathy2,3 and TTR-related cardiomyopathy4.
- Immunogen:
- UPR (Unfolded Protein Response)
- Molecular Weight:
- 308.12
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
