NLRP3i
Product Sizes
20 mg
£149.00
10-3672-20MG
100 mg
£226.00
10-3672-100MG
About this Product
- SKU:
- 10-3672
- Additional Names:
- JC121
- CAS Number:
- 16673-34-0
- Extra Details:
- NLRP3 inflammasome inhibitor which likely acts via interfering with the formation of the NLRP3 inflammasome complex and which exhibits promising in vivo protective activities in mouse acute myocardial infarction models. It blocks ASC aggregation, blocks the release of IL-1 and the activation of caspase-1 in macrophages expressing constitutively active NLRP3 but does not directly inhibit caspase-1.1,2 Limits infarct size after myocardial ischemia-reperfusion as well as leukocyte infiltration in a peritonitis model in mice.2
- Immunogen:
- Inflammasome
- Molecular Weight:
- 368.84
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
