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Proteins and Peptides

4-Octyl itaconate

Product Sizes
20 mg
£149.00
10-3573-20MG
100 mg
£195.00
10-3573-100MG
About this Product
SKU:
10-3573
CAS Number:
3133-16-2
Extra Details:
4-Octyl itaconate is a cell-permeable analog of itaconic acid which activates the anti-inflammatory transcription factor Nrf2 via alkylation of KEAP1.1 It inhibits various forms of cell death including ferroptosis2 and gasdermin B-mediated pyroptosis3 while inducing secretion of anti-inflammatory proteins4 and promoting a wound-resolving phenotype in pro-inflammatory macrophages5.
Immunogen:
Transcription factor
Molecular Weight:
242.32
Physical State:
Solid
Purity:
>98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules