AA43279
Product Sizes
5 mg
£182.00
10-3503-5MG
25 mg
£332.00
10-3503-25MG
About this Product
- SKU:
- 10-3503
- Extra Details:
- Selective Nav1.1activator. In HEK-293 cells expressing human Nav1.1 channels AA43279 increased the Nav1.1-mediated current in a concentration dependent manner (EC50=9.5 uM). In rat hippocampal brain slices it increased the firing activity parvalbumin-expressing, fast-spiking GABAergic interneurons and increased the spontaneous inhibitory post-synaptic currents recorded from pyramidal neurons. It displayed anticonvulsant activity in vivo. Important tool compound for exploring the physiology of Nav1.1 channels.1
- Molecular Weight:
- 248.30
- Physical State:
- Solid
- Purity:
- 97%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Manufacturer's Data Sheet:https://focusbiomolecules.com/ions-and-other-channels/aa43279-nav1-1-activator/