T0901317
Product Sizes
10 mg
£149.00
10-3361-10MG
50 mg
£195.00
10-3361-50MG
About this Product
- SKU:
- 10-3361
- CAS Number:
- 293754-55-9
- Extra Details:
- Potent high affinity liver X receptor (LXRA Alpha and B Beta) agonist, EC50~50 nM.1 Upregulates expression of ABCA1, a reverse cholesterol transporter, resulting in inhibition of cholesterol absorption. Inverse agonist at CAR.2 T0901317 was also shown to be an FXR agonist at lower potency than LXR thus appropriate controls must be employed when using this compound as a pharmacological tool.3 Decreases amyloid beta production in a mouse model of Alzheimer's disease.4 Inhibits cellular senescence in endothelial cells.5
- Immunogen:
- Transcription factor
- Molecular Weight:
- 481.33
- Physical State:
- Solid
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
