Rucaparib phosphate
Product Sizes
5 mg
£168.00
10-3321-5MG
25 mg
£320.00
10-3321-25MG
About this Product
- SKU:
- 10-3321
- Additional Names:
- AG-14699|PF01367338
- CAS Number:
- 459868-92-9
- Extra Details:
- Rucaparib is a potent (Ki<5 nM) PARP1 inhibitor.1 Cytotoxic to human cancer cells or xenograft tumors with mutated or epigenetically silenced BRCA1/2.2 Demonstrates antiproliferative effects in 26 out of 39 ovarian cancer cell lines.3 Synergizes with other anticancer agents such as topotecan, carboplatin, doxorubicin, paclitaxel3 and temozolamide.4 Ameliorates the cardiotoxicity of doxorubicin.5 Recently approved for human use by the FDA.
- Immunogen:
- PARP
- Molecular Weight:
- 421.36
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
