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Proteins and Peptides

Leu-Leu-OMe HBr

Product Sizes
20 mg
£144.00
10-3220-20MG
100 mg
£195.00
10-3220-100MG
About this Product
SKU:
10-3220
Additional Names:
LLME
CAS Number:
16689-14-8
Extra Details:
Leu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4
Immunogen:
Lysosome
Molecular Weight:
339.27
Physical State:
Solid
Purity:
98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules