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Product Sizes
50 mg
£168.00
10-3035-50MG
250 mg
£291.00
10-3035-250MG
About this Product
SKU:
10-3035
Additional Names:
FR34235
CAS Number:
75530-68-6
Extra Details:
A novel DHP L-type Ca2+ channel blocker that also inhibits Syk.1 Blocks AB Beta production, APPB Beta secretion and reduces BACE-1 expression in CHO cells over-expressing AB Beta in vitro. Enhances clearance of AB Beta across the blood brain barrier in vivo. Reduces brain AB Beta levels in a mouse tauopathy model.1 Clinically useful antihypertensive agent.2 Has been shown to prevent cognitive decline in some clinical trials.3 Produces a protective effect on glutamate neurotoxicity in retinal ganglion cells, an effect not shared by other L-type Ca2+ channel blockers such as nifedipine and diltiazem.4
Immunogen:
Ion channel|Kinase
Molecular Weight:
385.38
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
Sell Sheet 1:
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