PAC-1
Product Sizes
5 mg
£129.00
10-2979-5MG
25 mg
£192.00
10-2979-25MG
About this Product
- SKU:
- 10-2979
- CAS Number:
- 315183-21-2
- Extra Details:
- PAC-1 is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3, EC50=0.22 uM.1 It is less potent at activating procaspase-7, EC50=4.5 uM. It induces apoptosis in a variety of cancer cell lines. The mechanism of activation involves sequestering inhibitory zinc ions thus allowing procaspase-3 to autoactivate.2 Sensitizes cancer cells to various chemotherapeutic agents.3
- Immunogen:
- Chelator|Protease
- Molecular Weight:
- 392.49
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
