Embelin
Product Sizes
10 mg
£153.00
10-2959-10MG
50 mg
£262.00
10-2959-50MG
About this Product
- SKU:
- 10-2959
- CAS Number:
- 550-24-3
- Extra Details:
- Inhibits the lysine acetyl transferase PCAF in vitro and in vivo (in vitro IC50=7.2 uM). Inhibits H3K9 acetylation in mouse liver tissue while leaving levels of H3K14, H4K8, H4K12 unchanged1. Also inhibits X-linked inhibitor of apoptosis (XIAP) (IC50 = 4.1 uM, competing with Smac peptide). Binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Induces apoptosis and alters gene expression profiles in breast cancer cells3. Possesses anti-inflammatory and analgesic activity in vivo4. Cell-permeable.
- Immunogen:
- Acetyltransferase
- Molecular Weight:
- 294.39
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
