Probucol
Product Sizes
1 g
£197.00
10-2679-1G
10 g
£197.00
10-2679-10G
About this Product
- SKU:
- 10-2679
- Additional Names:
- DH-581
- CAS Number:
- 23288-49-5
- Extra Details:
- Probucol (23288-49-5) is a unique antilipidemic drug which inhibits the oxidation of LDL cholesterol preventing the genesis of macrophage-derived foam cells and thus suppressing the formation of atherosclerotic vascular lesions.1 It inhibits ABCA1-mediated cholesterol efflux without influencing scavenger receptor (class B type 1)-mediated efflux.2 It enhances mitophagy and improves survival, locomotor function and dopaminergic neuron loss in zebrafish and fly models of mitochondrial damage.3 It attenuates NF-kB/NLRP3 signaling and augments Nrf-2-mediated antioxidant defense in nerve injury models.4 Improves learning and memory in aging mice.5 It protects neuronal cells against peroxide-induced damage and directly activates glutathione peroxidase-1.6
- Immunogen:
- Antioxidant|Inflammasome
- Molecular Weight:
- 516.84
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- Type:
- Buffers & General Consumables: Others
