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Product Sizes
1 mg
£139.00
10-2632-1MG
5 mg
£204.00
10-2632-5MG
About this Product
SKU:
10-2632
Additional Names:
1-deoxygalactonojirimycin|AT1001|DDIG|DGJ|GR181413
CAS Number:
75172-81-5
Extra Details:
Migalastat is a potent, selective, and orally available inhibitor of A Alpha-galactosidase A (IC50= 40 nM).1 It binds to mutant misfolded A Alpha-GalA shifting the folding behavior toward functional active conformation (pharmacological chaperone activity) followed by trafficking to the lysosomes.2 Migalastat is active broadly across species from Drosophila3 to human4. Clinically useful agent for Fabry disease.5
Immunogen:
Chaperone|Galactosidase
Molecular Weight:
199.63
Physical State:
Solid
Purity:
>98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors