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Product Sizes
1 mg
£134.00
10-2631-1MG
5 mg
£192.00
10-2631-5MG
About this Product
SKU:
10-2631
Additional Names:
PG490
CAS Number:
38748-32-2
Extra Details:
Possesses potent immunosuppressive and anti-inflammatory activity. Irreversibly inhibits eukaryotic transcription via covalent binding to XPB, a subunit of the transcription factor TFIIH.1 Blocks transactivation of NFK KappaB.2 Exhibits potent antiproliferative activity in 60 cancer cell lines (average IC50 = 12 nM) and synergizes with other anticancer agents.3 Inhibits the inflammatory response and remarkably decreases production of TNF-A Alpha, IL-1B Beta and IL-6 in a rat model of rheumatoid arthritis.4
Immunogen:
Transcription factor
Molecular Weight:
360.40
Physical State:
Solid
Purity:
98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Sell Sheet 1:
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Sell Sheet 2:
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