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Product Sizes
5 mg
£177.00
10-2626-5MG
25 mg
£339.00
10-2626-25MG
About this Product
SKU:
10-2626
Additional Names:
PF-02341066|PF-1066
CAS Number:
877399-52-5
Extra Details:
A potent and selective inhibitor of c-MET and ALK, IC50s=8 and 20 nM respectively.1 Inhibition of cell proliferation was associated with G1-S phase cell cycle arrest and induction of apoptosis in ALK-positive ALCL cells (IC50=30 nM) but not in ALK-negative lymphoma cells.1 Exhibits cytoreductive antitumor efficacy via antiproliferative and antiangiogenic mechanisms.2 Clinically useful anticancer agent.3
Immunogen:
Kinase
Molecular Weight:
450.34
Physical State:
Solid
Purity:
98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors