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Product Sizes
10 mg
£129.00
10-2618-10MG
50 mg
£197.00
10-2618-50MG
About this Product
SKU:
10-2618
Additional Names:
Bisphenol A diglycidyl ether
CAS Number:
1675-54-3
Extra Details:
PPARG Gamma antagonist with uM affinity in 3T3-L1 and 3T3-F442A preadipocyte cells. Selective over PPARD Delta and PPARA Alpha. Antagonizes the ability of rosiglitazone to stimulate transcriptional activity of PPARG Gamma and abolishes its anti-inflammatory effects in a mouse model1. Induces apoptosis via PPARG Gamma-independent mechanisms2. Induces adipogenesis in human and mouse mesenchymal stromal stem cells and in mouse 3T3-L1 preadipocytes at low nM concentrations via a PPARG Gamma independent mechanism3. Increases osteoblastogenesis and bone mass in a mouse model4. Active in vivo.
Immunogen:
Transcription factor
Molecular Weight:
340.41
Physical State:
Solid or oil
Purity:
95%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors