FAK inhibitor 14
Product Sizes
10 mg
£144.00
10-2547-10MG
50 mg
£224.00
10-2547-50MG
About this Product
- SKU:
- 10-2547
- Additional Names:
- Y15
- CAS Number:
- 4506-66-5
- Extra Details:
- Selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC50 = 1 uM), promotes cell detachment and inhibits cell adhesion in vitro. Exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo. Induces regression of pancreatic tumors2 and glioblastoma3. Displays antiangiogenic activity4.
- Immunogen:
- Kinase
- Molecular Weight:
- 284.02
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
