SC-560
Product Sizes
5 mg
£149.00
10-2531-5MG
25 mg
£238.00
10-2531-25MG
About this Product
- SKU:
- 10-2531
- CAS Number:
- 188817-13-2
- Extra Details:
- SC-560 is a highly selective (700-fold selective over COX-2) and potent (IC50 = 9 nM) inhibitor of cyclooxygenase-1(COX-1).1 SC-560 inhibited TNFa-induced PGE2 synthesis in neurons and, PGE2 and thromboxane A2 synthesis in human monocytes and platelets (IC50's = 1.8 nM and 2.5 nM respectively) indicating non-selective COX inhibition. SC-560 was able to inhibit PGE2 synthesis in COX-1-deficient neurons indicating a COX-1 independent mechanism. This unselective COX inhibition was only observed in whole cells - it remained COX-1 specific in cell lysates.2
- Immunogen:
- COX (Cyclooxygenase)
- Molecular Weight:
- 352.74
- Physical State:
- Solid
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
