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Product Sizes
5 mg
£168.00
10-2491-5MG
25 mg
£320.00
10-2491-25MG
About this Product
SKU:
10-2491
CAS Number:
1012054-59-9
Extra Details:
A novel hybrid dual-acting HDAC and receptor tyrosine kinase inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2, IC50 = 4.4, 2.4 and 15.7 nM respectively.1 It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors.1,2
Immunogen:
Kinase|Protein deacetylase
Molecular Weight:
434.49
Physical State:
Solid
Purity:
99%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors