Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Picropodophyllotoxin

Product Sizes
5 mg
£177.00
10-2189-5MG
25 mg
£358.00
10-2189-25MG
About this Product
SKU:
10-2189
CAS Number:
477-47-4
Extra Details:
Potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP1. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC50 ~ 1 nM1. Displays antiproliferative activity in numerous tumor cell lines, IC50 = 0.05 - 15 M2. Exhibits antiangiogenic activitiy3. Attenuates intimal hyperplasia after vascular injury4. Active in vivo.
Immunogen:
Cytoskeleton|Kinase
Molecular Weight:
414.42
Physical State:
Solid
Purity:
97%
Shipping Conditions:
Ambient
Storage Conditions:
RT
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors