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Product Sizes
5 mg
£158.00
10-2132-5MG
25 mg
£247.00
10-2132-25MG
About this Product
SKU:
10-2132
Additional Names:
LY-317615
CAS Number:
170364-57-5
Extra Details:
Potent and selective PKCB Beta inhibitor. IC50 = 6, 39, 83 and 110 nM, for PKCB Beta, PKCA Alpha, PKCG Gamma and PKCE Epsilon respectively.1 Induces apoptosis in multiple myeloma cell lines via inhibition of the AKT signaling pathway.2 Induces mitotic missegregation and preferential cytotoxicity in colorectal cancer cells with chromosomal instability.3 Attenuates ampheta-mine-stimulated dopamine efflux.4 Inhibits blood-brain barrier leakiness in a mouse model.5
Immunogen:
Kinase
Molecular Weight:
515.61
Physical State:
Solid
Purity:
99%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors