Dovitinib
Product Sizes
5 mg
£173.00
10-2129-5MG
25 mg
£301.00
10-2129-25MG
About this Product
- SKU:
- 10-2129
- Additional Names:
- CHIR258|TKI-258
- CAS Number:
- 405169-16-6
- Extra Details:
- Potent kinase inhibitor. Inhibits FLT3 (IC50 = 1 nM), c-KIT (IC50 = 2 nM), FGFR (IC50 = 8 nM), VEGFR1/2/3 (IC50 = 10 nM), PDGFRB Beta (IC50 = 27 nM), and CSF-1R (IC50 = 36 nM).1 Active in cell culture and in whole animals. Selectively blocks the growth B9 cells transformed by wild type, or activated mutant FGFR3. Induces apoptosis, or sensitizes cells to induction of apoptosis by other means in a variety of cancer cell lines.
- Immunogen:
- Kinase
- Molecular Weight:
- 392.43
- Physical State:
- Solid
- Purity:
- 99%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
