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Product Sizes
1 mg
£163.00
10-2114-1MG
5 mg
£243.00
10-2114-5MG
About this Product
SKU:
10-2114
Additional Names:
NSC-101088
CAS Number:
5119-48-2
Extra Details:
Displays potent antiangiogenesis activity inhibiting endothelial cell sprouting in vitro (IC50 = 12 nM) and in vivo.1 Potently inhibits NF-K KappaB activation by preventing TNFA Alpha-induced activation of IKKB Beta.2 Covalently binds to the intermediate filament protein, vimentin3 inducing its disassembly and serine 56 phosphorylation4. Inhibits reactive gliosis and blocks TNFA Alpha-mediated neuronal apoptosis in in vivo models.5
Immunogen:
Cytoskeleton
Molecular Weight:
470.60
Physical State:
Solid
Purity:
99%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
Sell Sheet 1:
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