Thiolutin
Product Sizes
1 mg
£158.00
10-2106-1MG
5 mg
£230.00
10-2106-5MG
About this Product
- SKU:
- 10-2106
- Additional Names:
- Acetopyrrothin
- CAS Number:
- 87-11-6
- Extra Details:
- Inhibits the deubiquitinating (DUB) activity of PSMD14 exhibiting potent antitumor activity in neck squamous cell carcinoma in vitro and in vivo1. Inhibits endothelial cell adhesion by perturbing HSP27 interactions with components of the actin and intermediate filament cytoskeleton2. Potently inhibits developmental angiogenesis in zebrafish2. Inhibits adhesion of endothelial cells to vitronectin (IC50=0.83 M) inhibiting tumor cell-induced angiogenesis in vivo3. Cell permeable. Active in vivo.
- Immunogen:
- Cytoskeleton|DUB (Deubiquitinating enzyme)
- Molecular Weight:
- 228.29
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
- Sell Sheet 2:
- View Sell Sheet Here
