Ionomycin
Product Sizes
1 mg
£147.00
10-2079-1MG
5 mg
£251.00
10-2079-5MG
About this Product
- SKU:
- 10-2079
- CAS Number:
- 56092-81-0
- Extra Details:
- Highly selective nonfluorescent calcium (Ca2+) ionophore.1 Induces a rapid rise in cytosolic Ca2+ in human neutrophils which is due to both release from cytosolic Ca2+ stores as well as Ca2+ influx.2 It activates (2 uM) and primes (20-200 nM) neutrophil NADPH oxidase2. Down regulates beta-catenin/Tcf signaling in a colon cancer cell line via suppressing the binding of Tcf to its specific DNA-binding site.3 In rat hepatoma cells, sub-lethal ionomycin activates the stress response by activating SAPK/JNK and HSF/HSE interaction leading to upregulation of HSP70 biosynthesis.4
- Immunogen:
- Ionophore
- Molecular Weight:
- 709.01
- Physical State:
- Solid or oil
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Sell Sheet 1:
- View Sell Sheet Here
