Itraconazole
Product Sizes
50 mg
£144.00
10-2033-50MG
250 mg
£224.00
10-2033-250MG
About this Product
- SKU:
- 10-2033
- Additional Names:
- Oriconazole|R51211
- CAS Number:
- 84625-61-6
- Extra Details:
- Itraconazole inhibits the conversion of lanosterol to ergosterol via inhibition of the 14-A Alpha demethylase, a cytochrome P-450 enzyme1. Clinically useful antifungal agent. It inhibits the proliferation of glioblastoma cells in vitro and in vivo by inducing autophagic progression via inhibiting the trafficking of cholesterol from late endosomes and lysosomes to the plasma membrane2. Inhibits the hedgehog pathway by binding to Smoothened (SMO) via a mechanism distinct from that of cyclopamine3. Inhibits angiogenesis via inhibiting the binding of VEGF to VEGFR24.
- Immunogen:
- Cytochrome/MDR|GPCR|Lysosome
- Molecular Weight:
- 705.63
- Physical State:
- Solid
- Purity:
- 98%
- Purification:
- HPLC Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Sell Sheet 1:
- View Sell Sheet Here
