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Product Sizes
5 mg
£163.00
10-1620-5MG
25 mg
£291.00
10-1620-25MG
About this Product
SKU:
10-1620
CAS Number:
133406-29-8
Extra Details:
A novel selective adenylyl cyclase 1 (AC1) inhibitor, IC50=2.3 uM . Inhibits calcium2+-stimulated cAMP accumulation in HEK cells stably transfected with AC11. It was also shown to inhibit AC1 stimulated by forskolin- and GA Alphas-coupled receptors in HEK-AC1 cells. It enhanced u-opioid receptor-mediated inhibition of AC1 but it blocked heterologous sensitization of AC1 caused by chronic u-opioid receptor activation.1 Displays analgesic properties in a mouse model of inflammatory pain.1
Immunogen:
Adenylyl cyclase
Molecular Weight:
297.95
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
RT
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors