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Product Sizes
5 mg
£182.00
10-1530-5MG
25 mg
£378.00
10-1530-25MG
About this Product
SKU:
10-1530
Additional Names:
G6
CAS Number:
82058-16-0
Extra Details:
A remarkably potent and selective JAK2 inhibitor (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 uM1. Suppresses JAK2-V617F-mediated human pathological cell growth in vitro and in vivo2 and is concomitant with the disruption of intracellular vimentin filaments3. Reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo4.
Immunogen:
Cytoskeleton|Kinase
Molecular Weight:
436.65
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors