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Product Sizes
1 mg
£139.00
10-1517-1MG
5 mg
£204.00
10-1517-5MG
About this Product
SKU:
10-1517
CAS Number:
114719-57-2
Extra Details:
A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 uM) and is less selective for Cdk6/D1 (IC50 = 3.4 uM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.
Immunogen:
Kinase
Molecular Weight:
306.75
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors