GPI-16552
Product Sizes
5 mg
£158.00
10-1502-5MG
25 mg
£281.00
10-1502-25MG
About this Product
- SKU:
- 10-1502
- CAS Number:
- 443794-40-9
- Extra Details:
- A novel potent inhibitor of poly(ADP-ribose) glycohydrolase (PARG), IC50=1.7 uM1. Pre or post ischemia treatment (40 mg/kg) with GPI-16552 reduces brain infarct volumes in a rat model of cerebral ischemia2. It modulates the inflammatory response to ischemia/reperfusion in a rat splanchnic artery occlusion model3 and reduces the degree of spinal cord inflammation and tissue injury after experimental spinal cord trauma4. Synergizes with temozolomide in decreasing melanoma cell invasion and metastatic spreading in mice injected with B16 melanoma cells5.
- Immunogen:
- PARP
- Molecular Weight:
- 502.62
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
