MitoBloCK-6
Product Sizes
5 mg
£158.00
10-1472-5MG
25 mg
£224.00
10-1472-25MG
About this Product
- SKU:
- 10-1472
- CAS Number:
- 303215-67-0
- Extra Details:
- Inhibits redox-regulated protein translocation into mitochondria. It attenuates the import of Erv1 substrates by inhibition of Erv1 oxidase activity (the import of Tim23 and AAC was decreased by ~50% at 20 uM). MitoBloCK-6 elucidated an unexpected role for Erv1 in the carrier import pathway, namely transferring substrates from the translocase of the outer membrane complex into the small Tim complexes. It impaired cardiac development in zebrafish embryos and induced apoptosis via the release of cytochrome c in human embryonic stem cells but not differentiated cells1.
- Immunogen:
- Cytochrome/MDR
- Molecular Weight:
- 357.24
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
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- Sell Sheet 2:
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- Sell Sheet 3:
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- Sell Sheet 4:
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