NSC405020
Product Sizes
5 mg
£149.00
10-1462-5MG
25 mg
£243.00
10-1462-25MG
About this Product
- SKU:
- 10-1462
- CAS Number:
- 7497-07-6
- Extra Details:
- Membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14's protumorigenic activity in vivo. (IC50 > 100 uM). Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2. Suppresses bone erosion in a c-Fos-deficient mouse model.2 Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells.3
- Immunogen:
- Protease
- Molecular Weight:
- 260.15
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
