GSK-1702934A
Product Sizes
5 mg
£158.00
10-1445-5MG
25 mg
£262.00
10-1445-25MG
About this Product
- SKU:
- 10-1445
- CAS Number:
- 924377-85-5
- Extra Details:
- TRPC3 activator. In whole-cell patch-clamp experiments in HEK293 cells transduced with recombinant human TRPC3 or TRPC6, GSK-1702934A activated the TRPC3 and TRPC6 current with EC50 of 0.08 uM and 0.44 uM respectively. In the rat cardiomyocyte-like cell line H9C2 GSK-1702934A (1uM) activated TRPC6-like current and was completely blocked by GSK-417651A. It transiently increased the perfusion pressure of isolated rat heart retrogradely perfused via aortic cannulation at 1uM.1 Induces pro-arrhythmic and inotropic effects in TRPC3-overexpressing monocytes.2
- Immunogen:
- Ion channel
- Molecular Weight:
- 396.53
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Sell Sheet 1:
- View Sell Sheet Here
