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Product Sizes
5 mg
£177.00
10-1429-5MG
25 mg
£343.00
10-1429-25MG
About this Product
SKU:
10-1429
Extra Details:
A selective Sirt2 inhibitor (IC50=15.5 uM) which does not inhibit Sirt1 or Sirt31. It down regulates cholesterol biosynthesis genes in primary striatal neurons1. Displays neuroprotective effects in Huntington's disease mouse models including improved motor function, extended survival and reduced brain atrophy all of which were associated with reduced aggregated mutant huntingtin2.
Molecular Weight:
437.36
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
RT
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors