CZC-54252
Product Sizes
5 mg
£182.00
10-1421-5MG
25 mg
£378.00
10-1421-25MG
About this Product
- SKU:
- 10-1421
- CAS Number:
- 1191911-27-9
- Extra Details:
- Novel, potent and selective inhibitor of the leucine-rich repeat kinase-2 (LRRK2), IC50 = 1.28 nM. Also inhibits G2019S mutant LRRK2, IC50 = 1.85 nM1. Attenuates the neuronal damage elicited by the action of LRRK2 G2019S mutant in primary human neurons (EC50 = 1 nM)1. The G2019S mutant is a common mutation found in familial Parkinson's disease patients2. Cell permeable.
- Immunogen:
- Kinase
- Molecular Weight:
- 541.46
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
