GSK-J4
Product Sizes
5 mg
£149.00
10-1394-5MG
25 mg
£204.00
10-1394-25MG
About this Product
- SKU:
- 10-1394
- CAS Number:
- 1373423-53-0
- Extra Details:
- Histone demethylase JMJD3/UTX inhibitor. Inhibits demethylation of histone H3K27. Reduces LPS-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 uM for the inhibition of TNFA Alpha release). Cell permeable, ethyl ester of GSK J11. Rescues newborn pups from embryonic lethality in BRAF knockin mice which recapitulate major features of RASopathies2.
- Immunogen:
- Protein demethylase
- Molecular Weight:
- 417.48
- Physical State:
- Solid
- Purity:
- 99%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
