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Product Sizes
5 mg
£173.00
10-1393-5MG
25 mg
£339.00
10-1393-25MG
About this Product
SKU:
10-1393
CAS Number:
1373422-53-7
Extra Details:
Potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. The COOH group confers cell impermeability and as such is useful as a standard in in vitro assays. A cell permeable ethyl ester analog is also available.
Immunogen:
Protein demethylase
Molecular Weight:
389.46
Physical State:
Solid
Purity:
99%
Shipping Conditions:
Ambient
Storage Conditions:
RT
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
Sell Sheet 1:
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