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Product Sizes
5 mg
£158.00
10-1335-5MG
25 mg
£281.00
10-1335-25MG
About this Product
SKU:
10-1335
CAS Number:
935693-62-2
Extra Details:
BIX-01294 is a selective inhibitor of G9a histone methyltransferase (G9aHMTase; IC50 = 1.7 uM) as well as GLP HMTase (IC50 = 38 uM) leading to a decrease in H3K9me2(histone H3 lysine 9 methylation) in vitro.1 BIX-01294 facilitates the reactivation of pluripotency genes and induces passive demethylation, thus promoting reprogramming. BIX-01294, in combination with BAY K8644 (a calcium channel agonist), was found to improve reprogramming efficiencies of Oct4-Klf4-(OK)-infected neural progenitor cells.3
Immunogen:
Protein methyltransferase
Molecular Weight:
600.02
Physical State:
Solid
Purity:
>98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
RT
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
Sell Sheet 1:
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Sell Sheet 2:
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