MLN4924
Product Sizes
1 mg
£182.00
10-1311-1MG
5 mg
£353.00
10-1311-5MG
About this Product
- SKU:
- 10-1311
- Additional Names:
- Pevonedistat
- Extra Details:
- Potent and selective NEDD8-activating enzyme (NAE) inhibitor1. It disrupts cullin-RING ligase-mediated protein turnover leading to apoptosis in human tumor cells. Suppresses the growth of human tumor xenografts in mice2. Upregulates PD-L1 expression and enhances the efficacy of immune checkpoint blockade in glioblastoma3. Modulates tumor microenvironment4. Cell permeable.
- Molecular Weight:
- 443.53
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://focusbiomolecules.com/cancer/mln4924-nedd8-activating-enzyme-inhibitor/