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Product Sizes
500 mg
£139.00
10-1268-500MG
2 g
£187.00
10-1268-2G
About this Product
SKU:
10-1268
Additional Names:
Ara-C|Arabinocytidine|Cytosine B Beta-D-Arabinofuranoside|U-19920A
CAS Number:
147-94-4
Extra Details:
A nucleoside analog that interferes with DNA synthesis and transcription, particularly in tumor cells.1,2 It Cellular enzymes convert it to its nucleotide form, Ara-CTP, which disrupts DNA and RNA synthesis when polymerases attempt to incorporate it.3,4 For the same reasons, it is also employed as an antiviral.5 It inhibits proliferation of a variety of leukemic cell lines (IC50s 16-72 nM), but is used primarily against acute myeloid leukemia (AML).6,7
Immunogen:
DNA|RNA
Molecular Weight:
243.22
Physical State:
Solid
Purity:
98%
Purification:
HPLC Purified
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules