PIT-1
Product Sizes
10 mg
£134.00
10-1192-10MG
50 mg
£216.00
10-1192-50MG
About this Product
- SKU:
- 10-1192
- CAS Number:
- 53501-41-0
- Extra Details:
- PH domain antagonist. Specifically blocks the binding of PIP3 to the Akt pleckstrin homology domain (IC50 = 31 uM). Suppresses PI3K-PDK1-Akt-dependent phosphorylation. Induces apoptosis in PTEN-deficient U87MG glioblastoma cells (IC50 = 37 uM)1. Inhibiting the binding of PIP3 to effector PH domains is new point of intervention in the PI3K signaling network2.
- Immunogen:
- Kinase
- Molecular Weight:
- 351.76
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
