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Proteins and Peptides

KB-R7943 mesylate

Product Sizes
10 mg
£163.00
10-1163-10MG
50 mg
£301.00
10-1163-50MG
About this Product
SKU:
10-1163
CAS Number:
182004-65-5
Extra Details:
KB-R7943 is a potent and selective inhibitor of the reversed Na+/Ca2+ exchanger (NCE or NCX; IC50's = 1.2-2.4 uM in cardiomyocytes, smooth muscle cells, NCX1-transfected fibroblasts1; 0.7uM in cultured rat forebrain2). KB-R7943 has also been shown to inhibit the mitochondrial Ca2+ uniporter (MCU) - Ki = 5.5 uM.3 Recently shown to inhibit complex I in the mitochondrial respiratory chain (IC50 = 11.4 uM) and block NMDA receptors (IC50 = 13.4 uM).4
Immunogen:
Ion channel
Molecular Weight:
427.49
Physical State:
Solid
Purity:
98%
Shipping Conditions:
Ambient
Storage Conditions:
RT
Supplier:
Focus Biomolecules
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
Sell Sheet 1:
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Sell Sheet 2:
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