Rapamycin
Product Sizes
10 mg
10-1104-10MG
10 mM (in 1 ml DMSO)
10-1104-10MM(IN1MLDMSO)
50 mg
10-1104-50MG
About this Product
- SKU:
- 10-1104
- Additional Names:
- AY-22989|NSC-226080|Rapamune|Sirolimus|WY-090217
- CAS Number:
- 53123-88-9
- Extra Details:
- Clinically useful immunosuppressant. Inhibits the response to interleukin-2 blocking activation of T- and B-cells.1 Rapamycin forms a complex with cytosolic FK-binding protein 12 (FKB12) that binds to mTOR Complex1(mTORC1) inhibiting the mammalian target of rapamycin (mTOR).2 Also binds to mTORC2 leading to decreased glucose tolerance and insensitivity to insulin.3 Induces autophagy.4
- Immunogen:
- Antibiotic|Kinase|PPIase
- Molecular Weight:
- 914.17
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
