SKF-96365
Product Sizes
5 mg
£163.00
10-1068-5MG
25 mg
£301.00
10-1068-25MG
About this Product
- SKU:
- 10-1068
- CAS Number:
- 130495-35-1
- Extra Details:
- SKF-96365 (130495-35-1) was originally described as a selective blocker of receptor-mediated calcium entry (RMCE), IC50s= 8.5 and 11.7 uM for ADP- and thrombin-stimulated platelets respectively.1 TRPC channels have been shown to mediate RMCE2 and are believed to be the major target of SKF3. In rat vascular smooth muscle Ca entry was reduced by 10 uM SKF which was attributed to TRPC3.4 It has also been shown to inhibit L-type Ca channels.1 More recently it has been demonstrated to be a potent blocker of LVA hCaV3.1 T-type Ca channels, IC50=563 nM (state independent).5 Thus caution should be exercised when using SKF as a sole agent and appropriate controls are recommended.
- Immunogen:
- Ion channel
- Molecular Weight:
- 366.46∙36.46
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Sell Sheet 1:
- View Sell Sheet Here
- Sell Sheet 2:
- View Sell Sheet Here
